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Structure of 152937-04-7
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2-Bromo-6-fluoro-benzothiazole features a uniquely activated aromatic core with complementary halogen substituents, enabling direct functionalization in cross-coupling reactions. The ortho-fluoro and bromo groups facilitate selective Pd-catalyzed transformations, while the benzothiazole scaffold imparts enhanced stability and electron-deficient character. This compound serves as a key building block for bioactive heterocycles and advanced materials.
2-Bromo-6-fluoro-benzothiazole serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its complementary halogen reactivity. The bromo group facilitates Suzuki, Stille, and Negishi couplings, while the fluorine substituent enhances metabolic stability and modulates electronic properties. Its bench-stable crystalline form simplifies handling and purification, making it well-suited for modular synthesis of biologically active heterocycles and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: