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Structure of 1526564-53-3
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3-Bromo-2-fluoro-5-nitrobenzoic acid features a trifunctional aromatic core enabling direct coupling in late-stage diversification. The electron-deficient ring enhances reactivity in cross-coupling and nucleophilic substitution processes. This bench-stable, moisture-tolerant reagent integrates readily into synthetic sequences requiring halogenated nitroaromatic building blocks.
3-Bromo-2-fluoro-5-nitrobenzoic acid serves as a versatile building block for the synthesis of substituted aromatic scaffolds. Its orthogonal reactivity profile—combining halogen (Br), fluorine (F), and nitro (NO₂) functionalities with a carboxylic acid group—enables selective functionalization in late-stage diversification. The molecule exhibits good bench stability and facilitates efficient cross-coupling, nucleophilic substitution, and reduction sequences, making it valuable in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: