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Structure of 1153279-80-1
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5-Bromo-2-fluoro-3-nitrobenzoic acid features a densely functionalized aromatic core with bromine, fluorine, and nitro groups positioned for orthogonal reactivity. This electron-deficient scaffold enables direct coupling in cross-coupling or nucleophilic substitution protocols. The carboxylic acid moiety provides a handle for derivatization, while the halogen atoms facilitate selective metal-catalyzed transformations under mild conditions. Bench-stable and moisture-tolerant, this compound serves as a high-value building block in medicinal chemistry and materials synthesis.
5-Bromo-2-fluoro-3-nitrobenzoic acid serves as a versatile building block for the synthesis of substituted heterocycles and pharmaceutical intermediates. Its orthogonal reactivity profile—enabled by bromine, fluorine, and nitro groups—facilitates palladium-catalyzed cross-coupling, nucleophilic aromatic substitution, and controlled reduction sequences. The carboxylic acid group allows for direct derivatization or salt formation, enhancing solubility and purification. Bench-stable and compatible with standard synthetic workflows, it enables efficient access to complex aryl scaffolds in medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: