3-Aminopyridine-4-methanol

Name: 3-Aminopyridine-4-methanol
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CAS No. 152398-05-5
Cat. No. CS-0157313
Purity≥98%
MDL No.MFCD06658330

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General Information

CAS No. 152398-05-5
Cat. No. CS-0157313
Purity ≥98%
MDL No. MFCD06658330
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₈N₂O
Molecular Weight 124.14
Synonym(s) (3-Aminopyridin-4-yl)methanol
SMILES C1=C(CO)C(=CN=C1)N

Description

3-Aminopyridine-4-methanol integrates a primary amine and hydroxymethyl group on a pyridine scaffold, enabling versatile functionalization in medicinal chemistry. This bifunctional heterocycle supports conjugation strategies and serves as a key intermediate in targeted synthesis workflows.

Application

3-Aminopyridine-4-methanol serves as a versatile building block in medicinal chemistry, enabling the construction of heterocyclic scaffolds via nucleophilic substitution and coupling reactions. Its dual functionality—primary amine and primary alcohol—facilitates orthogonal derivatization, while the pyridine core enhances solubility and binding affinity in target-directed synthesis. Bench-stable and readily purified by crystallization, it functions efficiently in standard peptide coupling and transition-metal-catalyzed transformations.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

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Computational Chemistry Data

TPSA 59.14
LogP 0.1561
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Alcohol

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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3-Aminopyridine-4-methanol

CAS No. 152398-05-5

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