Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid

  • CAS No. 151734-02-0

  • Cat. No. CS-0090576
  • Purity≥95%
  • MDL No.MFCD17240900

*For research and further manufacturing use only, not for direct human use.

3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid|CS-0090576

Structure of 151734-02-0

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 151734-02-0
  • Cat. No. CS-0090576
  • Purity ≥95%
  • MDL No. MFCD17240900
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₄F₂N₂O₂
  • Molecular Weight 162.09
  • Synonym(s) None
  • SMILES O=C(C1=CNN=C1C(F)F)O

Description

This difluoromethyl-substituted pyrazole carboxylic acid features a polar, electron-deficient heterocycle paired with a moisture-tolerant difluoromethyl group, enabling robust integration into bioactive scaffolds and synthetic intermediates under standard conditions.

Application

3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid serves as a versatile building block for bioactive heterocycles, enabling direct incorporation of a difluoromethyl group adjacent to a pyrazole core. Its carboxylic acid functionality facilitates straightforward derivatization via amide, ester, or acyl chloride formation, while the difluoromethyl moiety enhances metabolic stability and modulates electronic properties. The compound exhibits good bench stability and compatibility with standard coupling reactions, supporting its use in medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P235-P261-P264-P270-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   65.98
  • LogP   1.0455
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 151734-02-0 sigma151734-02-0 manufacturer151734-02-0 price151734-02-0 structure151734-02-0 SDSbuy 151734-02-0151734-02-0 supplier151734-02-0 uses151734-02-0 molecular weightprice of 151734-02-0151734-02-0 chemical name formula of 151734-02-0
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label