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Structure of 1513-45-7
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4-(Trifluoromethoxy)benzenesulfonamide features a trifluoromethoxy group that enhances electron-withdrawal and metabolic stability, while the sulfonamide moiety provides strong hydrogen-bonding capacity. This combination enables robust integration into bioactive scaffolds for medicinal chemistry applications.
4-(Trifluoromethoxy)benzenesulfonamide serves as a versatile building block in medicinal chemistry, enabling the introduction of a strongly electron-withdrawing trifluoromethoxy group adjacent to a sulfonamide handle. Its stability under diverse reaction conditions and compatibility with common coupling protocols facilitate efficient incorporation into bioactive scaffolds, particularly in kinase inhibitors and enzyme modulators where enhanced metabolic stability and membrane permeability are desired.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362+P364
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Lot numbers can be found on the outside label of a product: