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CS-W001157 4
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5-Bromo-4-methoxy-1-methylpyridin-2(1H)-one

  • CAS No. 1509934-01-3

  • Cat. No. CS-0093862
  • Molecule weight218.05
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-Bromo-4-methoxy-1-methylpyridin-2(1H)-one|CS-0093862

Structure of 1509934-01-3

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General Information

  • CAS No. 1509934-01-3
  • Cat. No. CS-0093862
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈BrNO₂
  • Molecular Weight 218.05
  • Synonym(s) None
  • SMILES O=C1C=C(OC)C(Br)=CN1C

Description

5-Bromo-4-methoxy-1-methylpyridin-2(1H)-one features a brominated pyridinone core with a methoxy group at C4 and a methyl substituent at N1, delivering enhanced stability and tailored reactivity. This electron-deficient heterocycle integrates efficiently into cross-coupling reactions and serves as a key intermediate in medicinal chemistry for constructing bioactive scaffolds.

Application

5-Bromo-4-methoxy-1-methylpyridin-2(1H)-one serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its well-defined electrophilic bromine site. The methoxy and methyl groups provide orthogonal functional handles for further derivatization, while the pyridinone core ensures stability and solubility in common organic solvents. Its bench-stable nature and compatibility with standard reaction conditions make it ideal for modular synthesis of bioactive heterocycles and API intermediates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   31.23
  • LogP   1.1564
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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