8-bromoimidazo[1,2-a]pyridin-2-amine

Name: 8-bromoimidazo[1,2-a]pyridin-2-amine
Brand: ChemScene
Availability: InStock
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CAS No. 1509263-23-3
Cat. No. CS-W000746
Purity≥98%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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8-bromoimidazo[1,2-a]pyridin-2-amine|CS-W000746

Structure of 1509263-23-3

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General Information

CAS No. 1509263-23-3
Cat. No. CS-W000746
Purity ≥98%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₆BrN₃
Molecular Weight 212.05
Synonym(s) None
SMILES Nc1cn2cccc(Br)c2n1

Description

8-Bromoimidazo[1,2-a]pyridin-2-amine features a fused heterocyclic core with a bromine substituent at the 8-position and a primary amine at the 2-position. This combination enables direct functionalization in cross-coupling reactions and facilitates incorporation into bioactive scaffolds. The molecule exhibits good stability under standard conditions and serves as a key intermediate in medicinal chemistry.

Application

8-Bromoimidazo[1,2-a]pyridin-2-amine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to imidazo[1,2-a]pyridine scaffolds prevalent in kinase inhibitors and CNS-targeted therapeutics. The bromo group facilitates palladium-catalyzed cross-coupling reactions, while the amine functionality supports direct derivatization or salt formation, offering excellent bench stability and compatibility with standard purification methods.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

TPSA 43.32
LogP 1.679
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 0

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Imidazole compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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8-bromoimidazo[1,2-a]pyridin-2-amine

CAS No. 1509263-23-3

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