5-Bromopyrazolo[1,5-a]pyridin-2-amine

Name: 5-Bromopyrazolo[1,5-a]pyridin-2-amine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1507592-34-8
Cat. No. CS-0163542
Molecule weight212.05
Purity≥98%
MDL No.MFCD20258723

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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5-Bromopyrazolo[1,5-a]pyridin-2-amine|CS-0163542

Structure of 1507592-34-8

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General Information

CAS No. 1507592-34-8
Cat. No. CS-0163542
Purity ≥98%
MDL No. MFCD20258723
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₆BrN₃
Molecular Weight 212.05
Synonym(s) None
SMILES NC1=NN2C=CC(Br)=CC2=C1

Description

5-Bromopyrazolo[1,5-a]pyridin-2-amine features a brominated pyrazolopyridine core with a pendant amine, enabling direct functionalization in cross-coupling and medicinal chemistry. This electron-deficient heterocycle serves as a key scaffold for kinase inhibitors and bioactive compounds, offering high reactivity and stability under standard conditions.

Application

5-Bromopyrazolo[1,5-a]pyridin-2-amine serves as a versatile building block in medicinal chemistry, enabling direct incorporation into biologically active heterocycles. Its bromine atom facilitates palladium-catalyzed cross-coupling reactions, while the pyrazolopyridine core offers favorable metabolic stability and hydrogen-bonding capacity. The amine functionality supports derivatization via acylation or alkylation, enhancing scaffold diversity. This compound exhibits bench stability and compatibility with standard purification methods, making it well-suited for iterative synthesis campaigns in drug discovery programs.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

TPSA 43.32
LogP 1.679
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 0

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyrazole compounds

Key Words

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5-Bromopyrazolo[1,5-a]pyridin-2-amine

CAS No. 1507592-34-8

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