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CS-W001157 4
Total: USD 88.00

2-Cyano-N-ethylacetamide

  • CAS No. 15029-36-4

  • Cat. No. CS-0141694
  • Purity≥97%
  • MDL No.MFCD00118415

*For research and further manufacturing use only, not for direct human use.

2-Cyano-N-ethylacetamide|CS-0141694

Structure of 15029-36-4

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General Information

  • CAS No. 15029-36-4
  • Cat. No. CS-0141694
  • Purity ≥97%
  • MDL No. MFCD00118415
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₈N₂O
  • Molecular Weight 112.13
  • Synonym(s) 2-cyano-N-ethyl-ethanamide
  • SMILES O=C(CC#N)NCC

Description

2-Cyano-N-ethylacetamide features a dual functional group architecture: a nitrile moiety paired with an N-ethylamido linkage. This combination enables participation in nucleophilic addition reactions and facilitates integration into synthetic scaffolds requiring polar yet stable intermediates. The molecule exhibits robust bench stability under standard conditions, supporting reliable use in multistep transformations.

Application

2-Cyano-N-ethylacetamide serves as a versatile building block in synthetic organic chemistry, enabling efficient access to nitrile-containing heterocycles and functionalized acetonitrile derivatives. Its dual functionality—cyano and amide groups—supports diverse transformations including hydrolysis, nucleophilic addition, and cyclization reactions. The molecule exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis workflows in medicinal chemistry and process development.

Synthesis

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      2-Cyano-N-ethylacetamide|CS-0141694
      15029-36-4

    References

    • SHIONOGI and CO., LTD. Patent: EP1357111 A1, 2003 ; Location in patent: Page/Page column 58-59 ;
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    • In-stock
      2-Cyano-N-ethylacetamide|CS-0141694
      15029-36-4

    References

    • Zhou, Linna; Stewart, Gavin; Rideau, Emeline; Westwood, Nicholas J.; Smith, Terry K. Journal of Medicinal Chemistry, 2013 , vol. 56, # 3 p. 796 - 806

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   52.89
  • LogP   0.03618
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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