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CS-W001157 4
Total: USD 88.00

4-tert-Butoxy-4-oxobutanoic acid

  • CAS No. 15026-17-2

  • Cat. No. CS-W008838
  • Purity≥97%
  • MDL No.MFCD00273441

*For research and further manufacturing use only, not for direct human use.

4-tert-Butoxy-4-oxobutanoic acid|CS-W008838

Structure of 15026-17-2

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General Information

  • CAS No. 15026-17-2
  • Cat. No. CS-W008838
  • Purity ≥97%
  • MDL No. MFCD00273441
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₄O₄
  • Molecular Weight 174.20
  • Synonym(s) None
  • SMILES O=C(O)CCC(=O)OC(C)(C)C

Description

mono-tert-Butyl succinate can be prepared by refluxing a mixture of succinic anhydride and N-hydroxyl succinimide in the presence of dimethylaminopyridine and triethylamine in tert-butanol and toluene.mono-tert-Butyl succinate may be used in the preparation of:N-succinyl-L,L-diaminopimelic acid (SDAP)H3K9TSu (histone H3 lysine 9 thiosuccinyl) peptidetert-butyl 4-oxo-4-(4-tritylpiperazin-1-yl)butanoate

Synthesis

  • Route1
    • null|null
      15026-16-1
    • ~83%
    • In-stock
      4-tert-Butoxy-4-oxobutanoic acid|CS-W008838
      15026-17-2

    References

    • Nelson, Michael E.; Priestley, Nigel D. Journal of the American Chemical Society, 2002 , vol. 124, # 12 p. 2894 - 2902
  • Route2
    • null|null
      14734-25-9
    • ~70%
    • In-stock
      4-tert-Butoxy-4-oxobutanoic acid|CS-W008838
      15026-17-2

    References

    • Salomon, Claudio J.; Mata, Ernesto G.; Mascaretti, Oreste A. Journal of Organic Chemistry, 1994 , vol. 59, # 24 p. 7259 - 7266
  • Route3
    • In-stock
      Succinic anhydride|CS-0011581
      108-30-5
    • null|null
      75-65-0
    • ~80%
    • In-stock
      4-tert-Butoxy-4-oxobutanoic acid|CS-W008838
      15026-17-2

    References

    • Colombo, Raffaele; Mingozzi, Michele; Belvisi, Laura; Arosio, Daniela; Piarulli, Umberto; Carenini, Nives; Perego, Paola; Zaffaroni, Nadia; De Cesare, Michelandrea; Castiglioni, Vittoria; Scanziani, Eugenio; Gennari, Cesare Journal of Medicinal Chemistry, 2012 , vol. 55, # 23 p. 10460 - 10474

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   63.6
  • LogP   1.1929
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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