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Structure of 149554-29-0
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6-(Piperazin-1-yl)nicotinonitrile features a pyridine core functionalized with a nitrile group and a piperazine moiety, delivering enhanced solubility and hydrogen-bonding capacity. This combination enables efficient integration into medicinal chemistry scaffolds, particularly in kinase inhibitor design and bioactive heterocyclic systems.
6-(Piperazin-1-yl)nicotinonitrile serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling and cyclization protocols. Its nitrile group facilitates nucleophilic addition and amide formation, while the piperazine moiety provides solubility and hydrogen-bonding capacity. The molecule exhibits bench stability and compatibility with common reaction conditions, supporting efficient purification and integration into complex scaffolds.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 3439
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H312-H315-H319-H332-H335
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Precautionary Statements : P233-P261-P280-P301+P330+P331-P302+P352-P304+P340
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Lot numbers can be found on the outside label of a product: