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CS-W001157 4
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Gly-Gly-Leu

  • CAS No. 14857-82-0

  • Cat. No. CS-0101241
  • Purity≥97%
  • MDL No.MFCD00067447

*For research and further manufacturing use only, not for direct human use.

Gly-Gly-Leu|CS-0101241

Structure of 14857-82-0

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General Information

  • CAS No. 14857-82-0
  • Cat. No. CS-0101241
  • Purity ≥97%
  • MDL No. MFCD00067447
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₉N₃O₄
  • Molecular Weight 245.28
  • Synonym(s) H-Gly-Gly-Leu-OH
  • SMILES CC(C)C[C@@H](C(O)=O)NC(CNC(CN)=O)=O

Description

Gly-Gly-Leu is a tripeptide featuring a C-terminal leucine residue, offering enhanced metabolic stability and favorable solubility under physiological conditions. This sequence integrates readily into peptide-based drug candidates, serving as a structural motif for modulating bioavailability and proteolytic resistance in therapeutic development.

Synthesis

  • Route1
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      55260-11-2
    • ~%
    • In-stock
      Gly-Gly-Leu|CS-0101241
      14857-82-0

    References

    • Journal of Biological Chemistry, , vol. 173, p. 457,467
  • Route2
    • Methyl L-leucinate|CS-0093750
      2666-93-5
    • ~%
    • In-stock
      Gly-Gly-Leu|CS-0101241
      14857-82-0

    References

    • Journal of Biological Chemistry, , vol. 173, p. 457,467

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H317-H319
Precautionary Statements : P261-P264-P272-P280-P302+P352-P362+P364-P501

Quality Control

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Computational Chemistry Data

  • TPSA   121.52
  • LogP   -1.3232
  • H_Acceptors   4
  • H_Donors   4
  • Rotatable_Bonds   7

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