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CS-W001157 4
Total: USD 88.00

L-Phe-NCA

  • CAS No. 14825-82-2

  • Cat. No. CS-W022769
  • Purity≥95%
  • MDL No.MFCD03411306

*For research and further manufacturing use only, not for direct human use.

L-Phe-NCA|CS-W022769

Structure of 14825-82-2

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General Information

  • CAS No. 14825-82-2
  • Cat. No. CS-W022769
  • Purity ≥95%
  • MDL No. MFCD03411306
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₉NO₃
  • Molecular Weight 191.18
  • Synonym(s) (S)-4-Benzyloxazolidine-2,5-dione
  • SMILES O=C(N[C@H]1CC2=CC=CC=C2)OC1=O

Description

L-Phe-NCA enables efficient synthesis of well-defined polypeptides via ring-opening polymerization. This N-carboxyanhydride features a phenylalanine side chain that enhances hydrophobicity and structural integrity in the resulting polymer backbone, facilitating precise control over sequence and chain length under mild conditions.

Synthesis

  • Route1
    • 2,2,10,10-Tetramethyl-3,5,7,9-tetraoxaundecane-4,6,8-trione|CS-1700704
      24424-95-1
    • L-Phenylalanine Aspartame Impurity|CS-0229723
      63-91-2
    • ~25%
    • In-stock
      L-Phe-NCA|CS-W022769
      14825-82-2

    References

    • Nagai, Atsushi; Sato, Daisuke; Ishikawa, Junichi; Ochiai, Bungo; Kudo, Hiroto; Endo, Takeshi Macromolecules, 2004 , vol. 37, # 7 p. 2332 - 2334
  • Route2
    • null|null
      32315-10-9
    • L-Phenylalanine hydrochloride|CS-0201620
      17585-69-2
    • ~%
    • In-stock
      L-Phe-NCA|CS-W022769
      14825-82-2

    References

    • Synthetic Communications, , vol. 31, # 14 p. 2169 - 2175
  • Route3
    • L-Phenylalanine Aspartame Impurity|CS-0229723
      63-91-2
    • ~%
    • In-stock
      L-Phe-NCA|CS-W022769
      14825-82-2

    References

    • Journal of Organic Chemistry, , vol. 57, # 28 p. 7334 - 7338

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   55.4
  • LogP   0.8641
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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