N-Boc-Tris

Name: N-Boc-Tris
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 146651-71-0
Cat. No. CS-0115591
Purity≥95%
MDL No.MFCD14581676

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

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Structure of 146651-71-0

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General Information

CAS No. 146651-71-0
Cat. No. CS-0115591
Purity ≥95%
MDL No. MFCD14581676
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₁₉NO₅
Molecular Weight 221.25
Synonym(s) None
SMILES O=C(OC(C)(C)C)NC(CO)(CO)CO

Description

N-Boc-Tris features a triazine core functionalized with a Boc-protected amine, offering a stable, moisture-tolerant scaffold for modular synthesis. This bench-stable reagent integrates readily into multistep sequences, enabling efficient access to complex heterocyclic architectures through orthogonal deprotection strategies.

Application

N-Boc-Tris serves as a versatile, bench-stable building block for the synthesis of complex nitrogen-containing scaffolds. The Boc-protected triamine functionality enables sequential coupling reactions with diverse electrophiles, offering orthogonal reactivity for multi-step synthetic sequences. Its high solubility and ease of purification facilitate scalable applications in medicinal chemistry and process development workflows.

Synthesis

Route1
- In-stock
  
  24424-99-5
- In-stock
  
  77-86-1
- ~99%
- In-stock
  
  146651-71-0
References
- Jahani, Fatemeh; Tajbakhsh, Mahmood; Golchoubian, Hamid; Khaksar, Samad Tetrahedron Letters, 2011 , vol. 52, # 12 p. 1260 - 1264
Route2
- In-stock
  
  58632-95-4
- In-stock
  
  77-86-1
- ~78%
- In-stock
  
  146651-71-0
References
- Seto, Christopher T.; Mathias, John P.; Whitesides, George M. Journal of the American Chemical Society, 1993 , vol. 115, # 4 p. 1321 - 1329

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

TPSA 99.02
LogP -0.7732
H_Acceptors 5
H_Donors 4
Rotatable_Bonds 4

Other Classifications

Building Blocks Functional Group Boc

Building Blocks Functional Group Amine

Building Blocks Functional Group Alcohol

Building Blocks Skeleton Fatty chain compounds

Key Words

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CAS No. 146651-71-0

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