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CS-W001157 4
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H-Trp(Boc)-OH

  • CAS No. 146645-63-8

  • Cat. No. CS-W022755
  • Purity≥97%
  • MDL No.MFCD00237294

*For research and further manufacturing use only, not for direct human use.

H-Trp(Boc)-OH|CS-W022755

Structure of 146645-63-8

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General Information

  • CAS No. 146645-63-8
  • Cat. No. CS-W022755
  • Purity ≥97%
  • MDL No. MFCD00237294
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₂₀N₂O₄
  • Molecular Weight 304.34
  • Synonym(s) N-Indole-T-Butoxycarbonyl-L-Tryptophan
  • SMILES N[C@@H](CC1=CN(C(OC(C)(C)C)=O)C2=CC=CC=C12)C(O)=O

Description

H-Trp(Boc)-OH is a protected tryptophan derivative featuring a benzyloxycarbonyl group at the N-terminus and a Boc-protected side chain. This bench-stable amino acid intermediate facilitates efficient peptide coupling in solid-phase synthesis, enabling reliable incorporation of tryptophan residues with minimal epimerization.

Application

H-Trp(Boc)-OH serves as a key building block in peptide synthesis, offering a stable, bench-ready form of tryptophan with orthogonal protection. The Boc group enables efficient removal under mild acidic conditions, preserving the indole side chain integrity. This derivative facilitates reliable coupling reactions and is widely used in the construction of bioactive peptides and heterocyclic scaffolds requiring controlled functionalization.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   94.55
  • LogP   2.3789
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   3

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