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Structure of 14659-60-0
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Methyl 4-fluoro-2,6-dimethylbenzoate features a fluorinated aromatic core with strategically positioned methyl groups that enhance lipophilicity and metabolic stability. This electron-deficient ester serves as a key intermediate in medicinal chemistry, enabling direct incorporation into bioactive scaffolds through cross-coupling or nucleophilic substitution reactions under standard conditions.
Methyl 4-fluoro-2,6-dimethylbenzoate serves as a versatile building block in synthetic organic chemistry, offering a trifunctional scaffold for further derivatization. The methyl ester enables straightforward hydrolysis or reduction, while the ortho-methyl groups provide steric protection and enhanced stability. The meta-fluorine substituent facilitates nucleophilic aromatic substitution or transition-metal-catalyzed coupling reactions, making this compound well-suited for medicinal chemistry campaigns and heterocycle synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: