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Structure of 146462-25-1
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Methyl 6-(bromomethyl)picolinate features a bromomethyl group at the 6-position of a picolinate ester, enabling direct functionalization in synthetic transformations. This electrophilic handle facilitates efficient coupling reactions, particularly in palladium-catalyzed cross-couplings and nucleophilic substitutions. The molecule exhibits excellent stability under standard bench conditions and integrates readily into complex molecular architectures.
Methyl 6-(bromomethyl)picolinate serves as a versatile building block for constructing bioactive heterocycles and pharmaceutical intermediates. The bromomethyl group enables efficient nucleophilic substitution, facilitating the introduction of diverse amine- and thiol-based side chains. Its bench-stable nature and compatibility with standard coupling conditions make it well-suited for iterative synthesis workflows in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H302+H312+H332-H314
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Precautionary Statements : P260-P261-P264-P270-P271-P280-P301+P330+P331-P302+P352-P304+P340-P330-P362+P364-P363-P405-P501
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Lot numbers can be found on the outside label of a product: