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Structure of 146346-81-8
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This fluorenylmethoxycarbonyl-protected serine derivative features a tert-butyldimethylsilyl group that enhances stability and solubility during peptide synthesis. The orthogonal protection scheme enables selective deprotection, streamlining the incorporation of serine residues in complex sequences under standard conditions.
N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-O-(tert-butyldimethylsilyl)-L-serine serves as a bifunctional amino acid building block for peptide synthesis, enabling orthogonal protection of both the α-amino and hydroxyl side chain functionalities. The Fmoc group facilitates mild base-labile deprotection, while the TBDMS ether provides robust protection against nucleophiles and acidic conditions. Its bench-stable nature and compatibility with standard coupling protocols streamline sequence assembly and support efficient purification.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: