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CS-W001157 4
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1-(3-Aminoazetidin-1-yl)ethanone hydrochloride

  • CAS No. 1462921-50-1

  • Cat. No. CS-0052895
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1-(3-Aminoazetidin-1-yl)ethanone hydrochloride|CS-0052895

Structure of 1462921-50-1

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General Information

  • CAS No. 1462921-50-1
  • Cat. No. CS-0052895
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₁ClN₂O
  • Molecular Weight 150.61
  • Synonym(s) None
  • SMILES Cl.CC(=O)N1CC(N)C1

Description

This bench-stable ketone features a 3-aminoazetidinyl moiety that integrates readily into bioactive molecule scaffolds. The hydrochloride salt enhances solubility and handling, enabling efficient coupling under standard conditions for medicinal chemistry applications.

Application

1-(3-Aminoazetidin-1-yl)ethanone hydrochloride serves as a versatile building block for medicinal chemistry, enabling the rapid construction of nitrogen-containing heterocycles. The azetidine core offers enhanced metabolic stability and improved membrane permeability in bioactive molecules. Its amine functionality facilitates straightforward derivatization via acylation, alkylation, or coupling reactions, while the hydrochloride salt ensures excellent bench stability and ease of handling. This compound functions as a key intermediate in the synthesis of kinase inhibitors and other pharmaceutical scaffolds.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   46.33
  • LogP   -0.4024
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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