Lot numbers can be found on the outside label of a product:
Azido-C6-OH
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CAS No. 146292-90-2
- Cat. No. CS-0148603
- Purity≥95%
- MDL No.MFCD22577171
*For research and further manufacturing use only, not for direct human use.
Structure of 146292-90-2
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General Information
- CAS No. 146292-90-2
- Cat. No. CS-0148603
- Purity ≥95%
- MDL No. MFCD22577171
- Storage 4°C
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₆H₁₃N₃O
- Molecular Weight 143.19
- Synonym(s) None
- SMILES OCCCCCCN=[N+]=[N-]
Description
Azido-C6-OH features a terminal azide group appended to a six-atom aliphatic chain terminating in a hydroxyl moiety. This bifunctional handle enables efficient copper-free click chemistry while offering enhanced solubility and compatibility with aqueous reaction media. The hydroxyl terminus facilitates conjugation or derivatization, supporting modular synthesis in bioconjugation and materials science applications.
Application
Azido-C6-OH serves as a versatile bifunctional building block, enabling efficient conjugation via azide-alkyne cycloaddition while providing a readily accessible hydroxyl group for further derivatization. Its bench-stable nature and compatibility with standard protecting group strategies facilitate integration into complex synthetic sequences, particularly in the construction of functionalized heterocycles and bioconjugates.
Synthesis
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Route1
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4286-55-9 - ~98%
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In-stock
146292-90-2
References
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Li, Hao; Fahrenbach, Albert C.; Coskun, Ali; Zhu, Zhixue; Barin, Gokhan; Zhao, Yan-Li; Botros, Youssry Y.; Sauvage, Jean-Pierre; Stoddart, J. Fraser Angewandte Chemie - International Edition, 2011 , vol. 50, # 30 p. 6782 - 6788
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Route2
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In-stock
2009-83-8 - ~99%
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In-stock
146292-90-2
References
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Malkoch, Michael; Schleicher, Kristin; Drockenmuller, Eric; Hawker, Craig J.; Russell, Thomas P.; Wu, Peng; Fokin, Valery V. Macromolecules, 2005 , vol. 38, # 9 p. 3663 - 3678
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Route3
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1352550-67-4 - ~75%
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In-stock
146292-90-2
References
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Gu, Guofeng; Fang, Min; Du, Yuguo Carbohydrate Research, 2011 , vol. 346, # 17 p. 2801 - 2804
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Safety Information
Download SDS|
GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Quality Control
Computational Chemistry Data
- TPSA 68.99
- LogP 1.8494
- H_Acceptors 2
- H_Donors 1
- Rotatable_Bonds 6
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