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CS-W001157 4
Total: USD 88.00

Prop-1-en-2-ylboronic acid,97%(stabilized with TBC)

  • CAS No. 14559-87-6

  • Cat. No. CS-0175097
  • Purity≥97%
  • MDL No.MFCD02179500

*For research and further manufacturing use only, not for direct human use.

Prop-1-en-2-ylboronic acid,97%(stabilized with TBC)|CS-0175097

Structure of 14559-87-6

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General Information

  • CAS No. 14559-87-6
  • Cat. No. CS-0175097
  • Purity ≥97%
  • MDL No. MFCD02179500
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₇BO₂
  • Molecular Weight 85.90
  • Synonym(s) Boronic acid, (1-methylethenyl)-
  • SMILES C=C(B(O)O)C

Description

Prop-1-en-2-ylboronic acid, stabilized with TBC, features a reactive boronate moiety conjugated to a terminal alkene for efficient Suzuki-Miyaura coupling. This bench-stable reagent integrates readily into cross-coupling workflows under standard conditions, offering high functional group tolerance and reliable yields in C–C bond formation.

Application

Prop-1-en-2-ylboronic acid, 97% (stabilized with TBC) serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of vinyl-substituted arenes and heterocycles. The TBC stabilization enhances bench stability and simplifies handling, while the boronic acid functionality exhibits broad functional group tolerance and compatibility with standard aqueous workups. Its predictable reactivity facilitates reliable synthesis of conjugated systems relevant to pharmaceutical and materials chemistry.

Synthesis

  • Route1
    • null|null
      13291-18-4
    • ~98%
    • In-stock
      Prop-1-en-2-ylboronic acid,97%(stabilized with TBC)|CS-0175097
      14559-87-6

    References

    • Bristol-Myers Squibb Company Patent: US2007/3539 A1, 2007 ; Location in patent: Page/Page column 103 ; US 20070003539 A1
  • Route2
    • null|null
      121-43-7
    • null|null
      13291-18-4
    • ~%
    • In-stock
      Prop-1-en-2-ylboronic acid,97%(stabilized with TBC)|CS-0175097
      14559-87-6

    References

    • Bulletin de la Societe Chimique de France, , p. 2557 - 2564
  • Route3

    References

    • IDEMITSU LOSAN CO., LTD. Patent: US2011/315964 A1, 2011 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H315-H318-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   -0.4255
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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