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CS-W001157 4
Total: USD 88.00

m-PEG6-NHS ester

  • CAS No. 1449390-12-8

  • Cat. No. CS-0110039
  • Purity≥95%
  • MDL No.MFCD27977519

*For research and further manufacturing use only, not for direct human use.

m-PEG6-NHS ester|CS-0110039

Structure of 1449390-12-8

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General Information

  • CAS No. 1449390-12-8
  • Cat. No. CS-0110039
  • Purity ≥95%
  • MDL No. MFCD27977519
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₈H₃₁NO₁₀
  • Molecular Weight 421.44
  • Synonym(s) None
  • SMILES COCCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O

Description

m-PEG6-NHS ester offers a hydrophilic, linear PEG spacer with a reactive NHS ester for conjugation to primary amines. This derivative enables efficient coupling under physiological conditions, delivering stable amide bonds. The extended PEG chain enhances solubility and reduces non-specific binding in biological applications.

Application

m-PEG6-NHS ester serves as a versatile, water-soluble crosslinking reagent enabling efficient amide bond formation with primary amines under physiological conditions. Its six-ethylene glycol spacer provides enhanced solubility and reduced non-specific binding, while the NHS ester group offers high reactivity and stability during storage. Ideal for conjugating biomolecules, peptides, or drug candidates to surfaces or delivery systems with minimal aggregation.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   119.06
  • LogP   -0.2869
  • H_Acceptors   10
  • H_Donors   0
  • Rotatable_Bonds   19

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