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Structure of 1012785-51-1
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2,4-Dichloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidine features a highly reactive iodine at the 5-position, enabling efficient cross-coupling transformations. The electron-deficient pyrrolopyrimidine core integrates readily into pharmaceutical scaffolds, while the dichloro substitution enhances metabolic stability and modulates electronic properties for targeted bioactivity.
2,4-Dichloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidine serves as a versatile building block for constructing biologically active heterocycles, enabling palladium-catalyzed cross-coupling reactions with high efficiency. The dichloro and iodo substituents provide orthogonal reactivity for sequential functionalization, while the pyrrolo[2,3-d]pyrimidine core offers structural rigidity and favorable electronic properties. Its bench-stable crystalline form facilitates handling and purification, making it well-suited for medicinal chemistry campaigns and API intermediate synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: