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CS-W001157 4
Total: USD 88.00

1-Methyl-2-(methylthio)-1H-imidazole

  • CAS No. 14486-52-3

  • Cat. No. CS-0149178
  • Purity≥97%
  • MDL No.MFCD25959069

*For research and further manufacturing use only, not for direct human use.

1-Methyl-2-(methylthio)-1H-imidazole|CS-0149178

Structure of 14486-52-3

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General Information

  • CAS No. 14486-52-3
  • Cat. No. CS-0149178
  • Purity ≥97%
  • MDL No. MFCD25959069
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₈N₂S
  • Molecular Weight 128.20
  • Synonym(s) None
  • SMILES CSC1=NC=CN1C

Application

S-Methylmethimiazole serves as a reliable sulfur-containing heterocyclic building block, enabling efficient access to thiazole derivatives via standard cyclization protocols. Its bench-stable nature and tolerance to common functional groups facilitate straightforward incorporation into complex molecular architectures, making it a practical reagent for medicinal chemistry and process development workflows.

Synthesis

  • Route1
    • In-stock
      1-Methylimidazole|CS-W008580
      616-47-7
    • null|null
      74-88-4
    • ~80%
    • In-stock
      1-Methyl-2-(methylthio)-1H-imidazole|CS-0149178
      14486-52-3

    References

    • Roy, Gouriprasanna; Mugesh Journal of the American Chemical Society, 2005 , vol. 127, # 43 p. 15207 - 15217
  • Route2
    • In-stock
      1-Methylimidazole|CS-W008580
      616-47-7
    • null|null
      624-92-0
    • ~%
    • In-stock
      1-Methyl-2-(methylthio)-1H-imidazole|CS-0149178
      14486-52-3

    References

    • Chauviere, Gerard; Bouteille, Bernard; Enanga, Bertin; De Albuquerque, Cristina; Croft, Simon L.; Dumas, Michel; Perie, Jacques Journal of Medicinal Chemistry, 2003 , vol. 46, # 3 p. 427 - 440
  • Route3
    • null|null
      186581-53-3
    • In-stock
      Methimazole|CS-2149
      60-56-0
    • ~%
    • In-stock
      1-Methyl-2-(methylthio)-1H-imidazole|CS-0149178
      14486-52-3

    References

    • Roussel Uclaf Patent: US5663164 A1, 1997 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS08
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H317-H319-H361
Precautionary Statements : P280-P302+P352-P305+P351+P338

Quality Control

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Computational Chemistry Data

  • TPSA   17.82
  • LogP   1.142
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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