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CS-W001157 4
Total: USD 88.00

Bromo-PEG3-azide

  • CAS No. 1446282-43-4

  • Cat. No. CS-0114338
  • Purity≥97%
  • MDL No.MFCD25424113
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Bromo-PEG3-azide|CS-0114338

Structure of 1446282-43-4

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Description

Bromo-PEG3-azide is a bifunctional reagent featuring a reactive bromo group and a terminal azide, enabling site-specific conjugation in bioorthogonal chemistry. This PEG3 spacer provides enhanced solubility and reduced aggregation, while the azide moiety facilitates efficient copper-catalyzed or strain-promoted cycloaddition reactions. Designed for modular synthesis in drug delivery and probe development.

Application

Bromo-PEG3-azide serves as a versatile bifunctional linker for bioconjugation and polymer functionalization. The bromo group enables efficient coupling with nucleophilic sites such as amines or thiols, while the terminal azide supports reliable copper-catalyzed (CuAAC) or strain-promoted (SPAAC) cycloadditions. Its three-ethylene glycol spacer provides excellent solubility and reduced non-specific binding, enhancing performance in aqueous environments. This reagent offers robust stability under standard bench conditions and facilitates clean purification, making it ideal for synthesizing conjugates, probes, and functionalized materials in medicinal chemistry and materials science workflows.

General Information

  • CAS No. 1446282-43-4
  • Cat. No. CS-0114338
  • Purity ≥97%
  • MDL No. MFCD25424113
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₆BrN₃O₃
  • Molecular Weight 282.13
  • Synonym(s) None
  • SMILES BrCCOCCOCCOCCN=[N+]=[N-]

Computational Chemistry Data

  • TPSA   76.45
  • LogP   1.7414
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   11

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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