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CS-W001157 4
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6-Methoxy-3-methylisoquinoline

  • CAS No. 14446-31-2

  • Cat. No. CS-0152887
  • Purity≥98%
  • MDL No.MFCD01846013

*For research and further manufacturing use only, not for direct human use.

6-Methoxy-3-methylisoquinoline|CS-0152887

Structure of 14446-31-2

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General Information

  • CAS No. 14446-31-2
  • Cat. No. CS-0152887
  • Purity ≥98%
  • MDL No. MFCD01846013
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₁NO
  • Molecular Weight 173.21
  • Synonym(s) 6-Methoxy-3-Methyl-Isoquinoline
  • SMILES CC1=CC2=CC(=CC=C2C=N1)OC

Description

6-Methoxy-3-methylisoquinoline is a bench-stable, electron-rich heterocycle featuring a methoxy group at the 6-position and a methyl substituent at the 3-position. This structural motif enhances solubility and modulates reactivity in transition metal-catalyzed coupling processes. The compound serves as a key building block for bioactive alkaloids and functional materials.

Application

6-Methoxy-3-methylisoquinoline serves as a versatile heterocyclic building block in medicinal chemistry and synthetic organic research. Its electron-rich isoquinoline core, combined with ortho-directed substituents (methoxy at C6, methyl at C3), enables predictable regioselective functionalization. The compound exhibits bench stability, facilitates palladium-catalyzed cross-coupling reactions, and functions as a scaffold for bioactive molecule development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   22.12
  • LogP   2.55182
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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