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CS-W001157 4
Total: USD 88.00

(7-Methoxy-5-methylbenzo[b]thiophen-2-yl)boronic acid

  • CAS No. 1443531-60-9

  • Cat. No. CS-0063875
  • Purity≥95%
  • MDL No.MFCD26406768

*For research and further manufacturing use only, not for direct human use.

(7-Methoxy-5-methylbenzo[b]thiophen-2-yl)boronic acid|CS-0063875

Structure of 1443531-60-9

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General Information

  • CAS No. 1443531-60-9
  • Cat. No. CS-0063875
  • Purity ≥95%
  • MDL No. MFCD26406768
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₁BO₃S
  • Molecular Weight 222.07
  • Synonym(s) Boronic acid, B-(7-methoxy-5-methylbenzo[b]thien-2-yl)-
  • SMILES CC1=CC(OC)=C2C(C=C(B(O)O)S2)=C1

Description

This boronate moiety features a methoxy-substituted benzo[b]thiophene scaffold, offering enhanced solubility and stability under standard conditions. The para-methoxy and ortho-methyl groups tune electronic properties for efficient cross-coupling reactions. Ideal for constructing complex heterocyclic architectures in medicinal chemistry and materials science applications.

Application

(7-Methoxy-5-methylbenzo[b]thiophen-2-yl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl architectures. The boronic acid moiety exhibits excellent bench stability and tolerates a range of functional groups, facilitating direct incorporation into complex molecular frameworks. Its utility is particularly notable in the synthesis of heterocyclic scaffolds relevant to medicinal chemistry and materials science.

Safety Information

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GHS Pictogram :
GHS No : GHS02
Signal Word : Danger
UN#: 3230
Class : 4.1
Packing Group : -
Hazard Statements : H242
Precautionary Statements : P210-P220-P234-P280-P370+P378-P420-P501

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Computational Chemistry Data

  • TPSA   49.69
  • LogP   0.89812
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

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