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CS-W001157 4
Total: USD 88.00

(S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(allyloxy)-4-oxobutanoic acid

  • CAS No. 144120-53-6

  • Cat. No. CS-W017785
  • Purity≥95%
  • MDL No.MFCD00467715

*For research and further manufacturing use only, not for direct human use.

(S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(allyloxy)-4-oxobutanoic acid|CS-W017785

Structure of 144120-53-6

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General Information

  • CAS No. 144120-53-6
  • Cat. No. CS-W017785
  • Purity ≥95%
  • MDL No. MFCD00467715
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₂H₂₁NO₆
  • Molecular Weight 395.41
  • Synonym(s) None
  • SMILES O=C(O)C[C@@H](C(OCC=C)=O)NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O

Description

(R,R)-SINpEtHBF4 is a chiral NHC ligand developed in the Glorius Lab for use in Ru(II) catalyzed enantioselective hydrogenations. It has been employed for the regioselectivity asymmetric hydrogenation of quinoxalines, benzofurans, thiophenes, indolizines, isocoumarins and many other heterocycles.Product can be used with our benchtop hydrogen generator, H-Genie Lite (Z744083)

Synthesis

  • Route1
    • null|null
      144120-52-5
    • ~96%
    • In-stock
      (S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(allyloxy)-4-oxobutanoic acid|CS-W017785
      144120-53-6

    References

    • Ge, Jingyan; Li, Lin; Yao, Shao Q. Chemical Communications, 2011 , vol. 47, # 39 p. 10939 - 10941
  • Route2
    • In-stock
      Fmoc-D-Asp-OH|CS-W011842
      136083-57-3
    • null|null
      107-18-6
    • ~88%
    • In-stock
      (S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(allyloxy)-4-oxobutanoic acid|CS-W017785
      144120-53-6

    References

    • Nuijens, Timo; Cusan, Claudia; Kruijtzer, John A. W.; Rijkers, Dirk T. S.; Liskamp, Rob M. J.; Quaedflieg, Peter J. L. M. Synthesis, 2009 , # 5 p. 809 - 814
  • Route3

    References

    • Tetrahedron Letters, , vol. 34, # 10 p. 1549 - 1552

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   101.93
  • LogP   3.0976
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   8

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