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CS-W001157 4
Total: USD 88.00

2-Chloro-5-methylpyrimidin-4-amine

  • CAS No. 14394-70-8

  • Cat. No. CS-W002966
  • Purity≥98%
  • MDL No.MFCD02683249

*For research and further manufacturing use only, not for direct human use.

2-Chloro-5-methylpyrimidin-4-amine|CS-W002966

Structure of 14394-70-8

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General Information

  • CAS No. 14394-70-8
  • Cat. No. CS-W002966
  • Purity ≥98%
  • MDL No. MFCD02683249
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₆ClN₃
  • Molecular Weight 143.57
  • Synonym(s) CHLOROAMINOMETHYLPYRIMIDINE; 4-Amino-2-chloro-5-methylpyrimidine
  • SMILES NC1=NC(Cl)=NC=C1C

Description

2-Chloro-5-methylpyrimidin-4-amine features a chlorinated pyrimidine core with a methyl group at the 5-position and an amino function at C4, enabling direct incorporation into heterocyclic scaffolds. This electron-deficient heterocycle serves as a key building block for medicinal chemistry, particularly in kinase inhibitor and antiviral agent development. The compound exhibits good stability under standard bench conditions and facilitates efficient coupling reactions.

Synthesis

  • Route1

    References

    • WO2004/74278 A1, ; Page 31-33 ; WO 2004/074278 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   51.8
  • LogP   1.02062
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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