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CS-W001157 4
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cis-3-(Aminomethyl)-1-methylcyclobutanol

  • CAS No. 1438241-25-8

  • Cat. No. CS-0049703
  • Molecule weight115.17
  • Purity≥95%
  • MDL No.MFCD23105955

*For research and further manufacturing use only, not for direct human use.

cis-3-(Aminomethyl)-1-methylcyclobutanol|CS-0049703

Structure of 1438241-25-8

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General Information

  • CAS No. 1438241-25-8
  • Cat. No. CS-0049703
  • Purity ≥95%
  • MDL No. MFCD23105955
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₃NO
  • Molecular Weight 115.17
  • Synonym(s) cis-3-Hydroxy-3-Methylcyclobutane-1-MethaMine
  • SMILES C[C@@]1(O)C[C@H](CN)C1

Description

cis-3-(Aminomethyl)-1-methylcyclobutanol features a rigid cyclobutane scaffold with complementary stereochemistry, enabling precise spatial positioning of the aminomethyl and methyl groups. This configuration enhances binding affinity in target-directed synthesis. The primary amine facilitates conjugation and derivatization, while the bench-stable structure supports reliable handling under standard conditions.

Application

cis-3-(Aminomethyl)-1-methylcyclobutanol serves as a versatile chiral building block in medicinal chemistry, enabling the synthesis of cyclobutane-containing scaffolds with defined stereochemistry. Its pendant primary amine and hydroxyl groups offer orthogonal functionalization potential, facilitating conjugation or derivatization in multi-step syntheses. The compound exhibits good bench stability and is compatible with standard coupling and protection protocols, making it well-suited for use in API development and target-oriented synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   46.25
  • LogP   0.1061
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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