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CS-W001157 4
Total: USD 88.00

4-Methylpyrazolo[1,5-a]pyridine-3-carboxylic acid

  • CAS No. 143803-93-4

  • Cat. No. CS-0038235
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Methylpyrazolo[1,5-a]pyridine-3-carboxylic acid|CS-0038235

Structure of 143803-93-4

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General Information

  • CAS No. 143803-93-4
  • Cat. No. CS-0038235
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₈N₂O₂
  • Molecular Weight 176.17
  • Synonym(s) None
  • SMILES CC1=CC=CN2C1=C(C=N2)C(=O)O

Description

4-Methylpyrazolo[1,5-a]pyridine-3-carboxylic acid is a heterocyclic carboxylic acid featuring a fused pyrazolo-pyridine core with a methyl substituent at the 4-position. This scaffold delivers enhanced electronic density and metabolic stability, enabling direct integration into bioactive molecules. The carboxylic acid group facilitates conjugation via amide or ester linkages, supporting applications in medicinal chemistry and drug discovery workflows.

Application

4-Methylpyrazolo[1,5-a]pyridine-3-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and materials science applications. Its fused pyrazolo-pyridine core provides enhanced rigidity and π-conjugation, while the carboxylic acid group enables direct derivatization via amide formation, esterification, or metal salt coordination. The methyl substituent at the 4-position offers favorable steric and electronic modulation, improving solubility and metabolic stability in drug-like scaffolds. This compound exhibits excellent bench stability and facilitates purification by standard chromatographic methods, making it well-suited for high-throughput synthesis campaigns and API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   54.6
  • LogP   1.34092
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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