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Structure of 1434142-19-4
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tert-Butyl 7-ethynyl-2-azaspiro[3.5]nonane-2-carboxylate features a rigid spirocyclic scaffold with a terminal alkyne at the C7 position, enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC). This functionality integrates seamlessly into bioconjugation and medicinal chemistry workflows, offering precise spatial control and enhanced metabolic stability in complex molecular architectures.
tert-Butyl 7-ethynyl-2-azaspiro[3.5]nonane-2-carboxylate serves as a versatile spirocyclic building block for the synthesis of nitrogen-containing heterocycles, particularly in medicinal chemistry and target-oriented synthesis. The terminal alkyne functionality enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC), facilitating rapid access to triazole-linked scaffolds. The tert-butyl ester group offers stability under basic conditions and can be selectively removed after key transformations. This compound exhibits excellent bench stability, compatibility with diverse functional groups, and ease of purification—making it ideal for modular synthetic campaigns requiring robust, high-yielding coupling reactions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: