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CS-W001157 4
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Potassium trifluoro(oxetan-3-yl)borate

  • CAS No. 1430219-76-3

  • Cat. No. CS-W018996
  • Purity≥95%
  • MDL No.MFCD24843091

*For research and further manufacturing use only, not for direct human use.

Potassium trifluoro(oxetan-3-yl)borate|CS-W018996

Structure of 1430219-76-3

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General Information

  • CAS No. 1430219-76-3
  • Cat. No. CS-W018996
  • Purity ≥95%
  • MDL No. MFCD24843091
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₅BF₃KO
  • Molecular Weight 163.98
  • Synonym(s) None
  • SMILES F[B-](F)(F)C1COC1.[K+]

Description

Potassium trifluoro(oxetan-3-yl)borate delivers a stable, moisture-tolerant boronate handle ideal for cross-coupling reactions. The oxetane ring enhances solubility and metabolic stability, while the trifluoroborate moiety enables efficient Suzuki-Miyaura coupling under mild conditions. This reagent integrates seamlessly into complex molecule synthesis workflows.

Application

Potassium trifluoro(oxetan-3-yl)borate serves as a stable, bench-ready boron building block for Suzuki-Miyaura cross-coupling reactions. The oxetane ring imparts enhanced metabolic stability and favorable physicochemical properties, making it particularly useful in medicinal chemistry for constructing bioactive heterocyclic scaffolds. Its trifluoroborate functionality enables reliable coupling with aryl and vinyl halides under mild conditions, offering excellent functional group tolerance and straightforward purification.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   9.23
  • LogP   -1.7618
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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