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CS-W001157 4
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4-Bromo-3-fluoro-2-hydroxybenzaldehyde

  • CAS No. 1427373-29-2

  • Cat. No. CS-0196784
  • Molecule weight219.01
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Bromo-3-fluoro-2-hydroxybenzaldehyde|CS-0196784

Structure of 1427373-29-2

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General Information

  • CAS No. 1427373-29-2
  • Cat. No. CS-0196784
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄BrFO₂
  • Molecular Weight 219.01
  • Synonym(s) None
  • SMILES C1=CC(=C(C(=C1C=O)O)F)Br

Description

4-Bromo-3-fluoro-2-hydroxybenzaldehyde features a unique trifunctional aromatic scaffold integrating bromo, fluoro, and hydroxy groups adjacent to an aldehyde moiety. This electron-deficient benzaldehyde serves as a high-value building block for pharmaceutical intermediates and functional materials, offering enhanced reactivity in cross-coupling and derivatization processes under standard conditions.

Application

4-Bromo-3-fluoro-2-hydroxybenzaldehyde serves as a versatile building block in the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-hydroxy and aldehyde functionalities enable efficient cyclization reactions, while the bromo and fluoro substituents provide handles for palladium-catalyzed cross-coupling and modulate electronic properties. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for multi-step synthetic sequences in medicinal chemistry and process development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   2.1063
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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