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CS-W001157 4
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Methyl 5-chloropentanoate

  • CAS No. 14273-86-0

  • Cat. No. CS-0098043
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl 5-chloropentanoate|CS-0098043

Structure of 14273-86-0

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General Information

  • CAS No. 14273-86-0
  • Cat. No. CS-0098043
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₁ClO₂
  • Molecular Weight 150.60
  • Synonym(s) Valeric acid, 5-chloro-, methyl ester
  • SMILES O=C(OC)CCCCCl

Description

Methyl 5-chloropentanoate is a chlorinated ester featuring a linear five-carbon chain with a terminal methyl ester and a chlorine substituent at the γ-position. This configuration imparts enhanced reactivity in nucleophilic substitution processes, particularly under basic conditions. The molecule exhibits good solubility in common organic solvents and maintains stability under standard bench handling. Its structure enables efficient incorporation into synthetic intermediates for pharmaceutical and agrochemical applications.

Synthesis

  • Route1
    • null|null
      67-56-1
    • In-stock
      5-Chloropentanoic acid|CS-W022362
      1119-46-6
    • ~83%
    • In-stock
      Methyl 5-chloropentanoate|CS-0098043
      14273-86-0

    References

    • Vodovozova, E. L.; Mikhalev, I. I.; Rzhaninova, A. A.; Garaev, M. M.; Molotkovsky, Yul. G. Russian Journal of Bioorganic Chemistry, 1995 , vol. 21, # 9 p. 626 - 632 Bioorganicheskaya Khimiya, 1995 , vol. 21, # 9 p. 724 - 730
  • Route2
    • null|null
      67-56-1
    • null|null
      201230-82-2
    • null|null
      120-92-3
    • ~%
    • In-stock
      Dimethyl adipate|CS-W016017
      627-93-0
    • In-stock
      Methyl 5-chloropentanoate|CS-0098043
      14273-86-0

    References

    • Tetrahedron Letters, , vol. 41, # 17 p. 3021 - 3024
  • Route3
    • null|null
      67-56-1
    • In-stock
      5-Chloropentanenitrile|CS-W022361
      6280-87-1
    • ~%
    • In-stock
      Methyl 5-chloropentanoate|CS-0098043
      14273-86-0

    References

    • Journal of the American Chemical Society, , vol. 73, p. 1861

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H227-H315-H319-H335
Precautionary Statements : P210-P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P370+P378-P403-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   1.5685
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   4

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