(R)-4-tert-Butyl-2-oxazolidinone

Name: (R)-4-tert-Butyl-2-oxazolidinone
Brand: ChemScene
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CAS No. 142618-93-7
Cat. No. CS-0097463
Purity≥98%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(R)-4-tert-Butyl-2-oxazolidinone|CS-0097463

Structure of 142618-93-7

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Description

(R)-4-tert-Butyl-2-oxazolidinone is a bench-stable chiral auxiliary featuring a sterically hindered tert-butyl group that enhances configurational stability. This oxazolidinone integrates readily into asymmetric synthesis, enabling high diastereoselective transformations in natural product and pharmaceutical development.

Application

(R)-4-tert-Butyl-2-oxazolidinone serves as a robust chiral auxiliary in asymmetric synthesis, enabling stereoselective enolate formation and subsequent C–C bond construction. Its bench-stable, crystalline nature facilitates straightforward handling and purification. The oxazolidinone core exhibits excellent functional group tolerance and reliably delivers high diastereoselectivity in alkylation and aldol reactions, making it a practical choice for iterative synthetic strategies in medicinal chemistry and natural product synthesis.

General Information

CAS No. 142618-93-7
Cat. No. CS-0097463
Purity ≥98%
MDL No. None
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₁₃NO₂
Molecular Weight 143.18
Synonym(s) (4R)-4-tert-butyl-1,3-oxazolidin-2-one
SMILES O=C1N[C@H](C(C)(C)C)CO1

Computational Chemistry Data

TPSA 38.33
LogP 1.1409
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(R)-4-tert-Butyl-2-oxazolidinone

CAS No. 142618-93-7

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