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o5-Tert-butylo3a-ethyl1,2,3,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole-3a,5-dicarboxylate

  • CAS No. 1424939-88-7

  • Cat. No. CS-0309643
  • Molecule weight284.35
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

o5-Tert-butylo3a-ethyl1,2,3,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole-3a,5-dicarboxylate|CS-0309643

Structure of 1424939-88-7

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General Information

  • CAS No. 1424939-88-7
  • Cat. No. CS-0309643
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₄N₂O₄
  • Molecular Weight 284.35
  • Synonym(s) None
  • SMILES CCOC(=O)C12C(CNC2)CN(C(=O)OC(C)(C)C)C1

Description

o5-Tert-butylo3a-ethyl1,2,3,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole-3a,5-dicarboxylate features a sterically shielded tert-butyl group and an ethyl ester moiety that enhance stability and modulate reactivity. This hexahydrofused pyrrolidine scaffold serves as a rigid, electron-rich building block for complex alkaloid synthesis under standard bench conditions.

Application

o5-Tert-butylo3a-ethyl1,2,3,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole-3a,5-dicarboxylate serves as a versatile heterocyclic building block for the synthesis of pyrrolidine-based scaffolds. Its protected diacid functionality enables sequential functionalization, while the tert-butyl ester and ethyl ester groups offer orthogonal deprotection pathways. The molecule exhibits excellent bench stability and facilitates efficient purification, making it well-suited for iterative synthetic campaigns in medicinal chemistry and process development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   67.87
  • LogP   1.006
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   2

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