Benzyl (2S)-2-{8-amino-1-bromoimidazo[1,5-a]pyrazin-3-yl}pyrrolidine-1-carboxylate

Name: Benzyl (2S)-2-{8-amino-1-bromoimidazo[1,5-a]pyrazin-3-yl}pyrrolidine-1-carboxylate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1420478-88-1
Cat. No. CS-0049898
Purity≥97%
MDL No.MFCD30184899

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Benzyl (2S)-2-{8-amino-1-bromoimidazo[1,5-a]pyrazin-3-yl}pyrrolidine-1-carboxylate|CS-0049898

Structure of 1420478-88-1

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 1420478-88-1
Cat. No. CS-0049898
Purity ≥97%
MDL No. MFCD30184899
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₈H₁₈BrN₅O₂
Molecular Weight 416.27
Synonym(s) 1-Pyrrolidinecarboxylic acid, 2-(8-amino-1-bromoimidazo[1,5-a]pyrazin-3-yl)-, phenylmethyl ester, (2S)-
SMILES NC1=NC=CN2C(=NC(Br)=C12)[C@@H]1CCCN1C(=O)OCC1=CC=CC=C1

Description

Benzyl (2S)-2-{8-amino-1-bromoimidazo[1,5-a]pyrazin-3-yl}pyrrolidine-1-carboxylate is a chiral imidazopyrazine derivative featuring a brominated heterocyclic core and a protected pyrrolidine moiety. This scaffold integrates a reactive bromine atom with an amine-functionalized ring system, enabling downstream coupling reactions in medicinal chemistry. The benzyl ester group provides stability and facilitates selective deprotection under standard conditions. The stereochemistry at the pyrrolidine center ensures defined spatial orientation critical for target engagement in drug discovery applications.

Application

Benzyl (2S)-2-{8-amino-1-bromoimidazo[1,5-a]pyrazin-3-yl}pyrrolidine-1-carboxylate serves as a versatile building block for the synthesis of imidazopyrazine-containing pharmaceuticals. The molecule combines a bromo-imidazopyrazine core with a chiral pyrrolidine moiety, enabling efficient late-stage functionalization via Pd-catalyzed cross-coupling reactions. Its benzyl carbamate group provides excellent stability and ease of purification, while the 8-amino functionality allows for further derivatization. This compound is particularly valuable in medicinal chemistry campaigns targeting kinase inhibitors and antiviral agents.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 85.75
LogP 3.5477
H_Acceptors 6
H_Donors 1
Rotatable_Bonds 3

Other Classifications

Building Blocks Functional Group Ester

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Aliphatic heterocycle compounds Pyrrolidine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Imidazole compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

1420478-88-1 sigma1420478-88-1 manufacturer1420478-88-1 price1420478-88-1 structure1420478-88-1 SDSbuy 1420478-88-11420478-88-1 supplier1420478-88-1 uses1420478-88-1 molecular weightprice of 1420478-88-11420478-88-1 chemical name formula of 1420478-88-1

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Benzyl (2S)-2-{8-amino-1-bromoimidazo[1,5-a]pyrazin-3-yl}pyrrolidine-1-carboxylate

CAS No. 1420478-88-1

Recommended Products