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CS-W001157 4
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1-Oxa-7-azaspiro[4.4]nonane hydrochloride

  • CAS No. 1419590-81-0

  • Cat. No. CS-0052417
  • Purity≥97%
  • MDL No.MFCD28502507

*For research and further manufacturing use only, not for direct human use.

1-Oxa-7-azaspiro[4.4]nonane hydrochloride|CS-0052417

Structure of 1419590-81-0

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General Information

  • CAS No. 1419590-81-0
  • Cat. No. CS-0052417
  • Purity ≥97%
  • MDL No. MFCD28502507
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₄ClNO
  • Molecular Weight 163.65
  • Synonym(s) 1-oxa-7-azaspiro[4.4]nonane hydrochlorid
  • SMILES Cl.C1COC2(CCNC2)C1

Description

This spirocyclic heterocycle features a rigid, three-dimensional scaffold with embedded oxygen and nitrogen atoms, delivering enhanced metabolic stability and improved solubility. The hydrochloride salt form ensures excellent crystallinity and handling ease, making it ideal for medicinal chemistry applications requiring defined conformational restraint and favorable physicochemical properties.

Application

1-Oxa-7-azaspiro[4.4]nonane hydrochloride serves as a versatile heterocyclic building block for medicinal chemistry, enabling efficient access to spirocyclic scaffolds prevalent in bioactive molecules. Its stable, crystalline form facilitates handling and purification, while the embedded amine and ether functionalities offer orthogonal reactivity for downstream functionalization. Functions effectively in standard coupling and alkylation protocols, supporting rapid diversification in lead optimization campaigns.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   21.26
  • LogP   0.9507
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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