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CS-W001157 4
Total: USD 88.00

tert-Butyl (4-(trifluoromethyl)phenyl)carbamate

  • CAS No. 141940-37-6

  • Cat. No. CS-M2831
  • Purity≥98%
  • MDL No.MFCD09859792

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (4-(trifluoromethyl)phenyl)carbamate|CS-M2831

Structure of 141940-37-6

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General Information

  • CAS No. 141940-37-6
  • Cat. No. CS-M2831
  • Purity ≥98%
  • MDL No. MFCD09859792
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₄F₃NO₂
  • Molecular Weight 261.24
  • Synonym(s) Tert-butyl N-[4-(trifluoromethyl)phenyl]carbamate
  • SMILES CC(C)(C)OC(NC1=CC=C(C(F)(F)F)C=C1)=O

Synthesis

  • Route1
    • 4-(Trifluoromethyl)aniline Leflunomide Impurity|CS-0229655
      455-14-1
    • In-stock
      Di-tert-butyl dicarbonate|CS-0017817
      24424-99-5
    • ~92%
    • In-stock
      tert-Butyl (4-(trifluoromethyl)phenyl)carbamate|CS-M2831
      141940-37-6

    References

    • WO2009/21696 A1, ; Page/Page column 68 ; WO 2009/021696 A1
  • Route2

    References

    • Tetrahedron Letters, , vol. 51, # 33 p. 4445 - 4448

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.33
  • LogP   4.0524
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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