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CS-W001157 4
Total: USD 88.00

3-Isopropylpyridin-2(1H)-one

  • CAS No. 1417519-11-9

  • Cat. No. CS-0534758
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Isopropylpyridin-2(1H)-one|CS-0534758

Structure of 1417519-11-9

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General Information

  • CAS No. 1417519-11-9
  • Cat. No. CS-0534758
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁NO
  • Molecular Weight 137.18
  • Synonym(s) 2-Hydroxy-3-(iso-propyl)pyridine
  • SMILES O=C1NC=CC=C1C(C)C

Description

3-Isopropylpyridin-2(1H)-one features a sterically hindered isopropyl group at the 3-position, enhancing its stability and modulating reactivity. The pyridinone core provides a hydrogen-bonding scaffold ideal for coordination and molecular recognition. This bench-stable compound integrates readily into synthetic sequences requiring a tunable nitrogen-containing heterocycle.

Application

3-Isopropylpyridin-2(1H)-one serves as a versatile scaffold in medicinal chemistry, enabling efficient access to bioactive heterocycles through established functionalization pathways. Its pyridinone core exhibits favorable bench stability and compatibility with common coupling reactions, facilitating rapid diversification via C–H activation or nucleophilic substitution. The isopropyl group enhances lipophilicity and metabolic stability, making it a practical building block for lead optimization campaigns.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

Quality Control

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Computational Chemistry Data

  • TPSA   32.86
  • LogP   1.4983
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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