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CS-W001157 4
Total: USD 88.00

Lenalidomide-OH

  • CAS No. 1416990-08-3

  • Cat. No. CS-0112251
  • Purity≥95%
  • MDL No.MFCD31794971

*For research and further manufacturing use only, not for direct human use.

Lenalidomide-OH|CS-0112251

Structure of 1416990-08-3

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General Information

  • CAS No. 1416990-08-3
  • Cat. No. CS-0112251
  • Purity ≥95%
  • MDL No. MFCD31794971
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₂N₂O₄
  • Molecular Weight 260.25
  • Synonym(s) None
  • SMILES O=C(C(N(CC1=C2C=CC(O)=C1)C2=O)CC3)NC3=O

Description

Lenalidomide-OH features a hydroxyl-modified imide scaffold that enhances solubility and metabolic stability compared to parent lenalidomide. This derivative integrates readily into targeted protein degradation workflows, offering improved handling under standard bench conditions while maintaining potent immunomodulatory activity.

Application

Lenalidomide-OH serves as a key synthetic intermediate for immunomodulatory drug derivatives, enabling straightforward access to the thalidomide scaffold. Its hydroxyl functionality enhances solubility and provides a handle for further functionalization via esterification or coupling reactions. The compound exhibits bench stability and compatibility with standard peptide and heterocyclic synthesis protocols, facilitating efficient route development in medicinal chemistry campaigns targeting hematological malignancies.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P233-P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   86.71
  • LogP   -0.4067
  • H_Acceptors   6
  • H_Donors   2
  • Rotatable_Bonds   1

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