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Structure of 1415241-98-3
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This boronate-functionalized thiazole integrates readily into Suzuki-Miyaura cross-coupling reactions under mild conditions. The trifluoromethyl group imparts enhanced electron-withdrawing character and metabolic stability, while the tetramethylcycloborate moiety ensures high reactivity and bench-stable handling.
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)thiazole serves as a versatile boronate building block in Suzuki-Miyaura cross-coupling reactions. The trifluoromethyl group imparts enhanced metabolic stability and lipophilicity, while the pinacol boronate moiety ensures excellent bench stability and compatibility with diverse reaction conditions. This compound facilitates efficient construction of biaryl and heteroaryl scaffolds common in pharmaceutical research and enables straightforward purification via standard chromatographic methods.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362
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Lot numbers can be found on the outside label of a product: