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CS-W001157 4
Total: USD 88.00

(1S,2R)-2-Fluorocyclopropan-1-amine hydrochloride

  • CAS No. 141042-20-8

  • Cat. No. CS-0143340
  • Purity≥97%
  • MDL No.MFCD19207082

*For research and further manufacturing use only, not for direct human use.

(1S,2R)-2-Fluorocyclopropan-1-amine hydrochloride|CS-0143340

Structure of 141042-20-8

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General Information

  • CAS No. 141042-20-8
  • Cat. No. CS-0143340
  • Purity ≥97%
  • MDL No. MFCD19207082
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₇ClFN
  • Molecular Weight 111.55
  • Synonym(s) None
  • SMILES N[C@@H]1[C@H](F)C1.Cl

Description

This fluorinated cyclopropanamine derivative features a strained three-membered ring system with stereochemically defined (1S,2R) configuration. The pendant amine group, delivered as the hydrochloride salt, enhances solubility and stability under standard conditions. This scaffold serves as a key building block in medicinal chemistry, particularly for probing conformationally restricted bioactive molecules.

Application

(1S,2R)-2-Fluorocyclopropan-1-amine hydrochloride serves as a conformationally constrained building block for medicinal chemistry, enabling the introduction of stereo-defined fluorinated cyclopropyl motifs into bioactive molecules. The compound exhibits excellent bench stability, facilitates direct incorporation into peptide and heterocyclic scaffolds, and demonstrates broad compatibility with standard amine functionalization protocols. Its defined stereochemistry supports reproducible synthetic outcomes in target-oriented synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   0.4773
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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