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CS-W001157 4
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tert-Butyl (3-methylazetidin-3-yl)carbamate hydrochloride

  • CAS No. 1408076-37-8

  • Cat. No. CS-0045530
  • Purity≥97%
  • MDL No.MFCD20809861

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (3-methylazetidin-3-yl)carbamate hydrochloride|CS-0045530

Structure of 1408076-37-8

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General Information

  • CAS No. 1408076-37-8
  • Cat. No. CS-0045530
  • Purity ≥97%
  • MDL No. MFCD20809861
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₉ClN₂O₂
  • Molecular Weight 222.71
  • Synonym(s) tert-butyl N-(3-methylazetidin-3-yl)carbamate hydrochloride
  • SMILES O=C(OC(C)(C)C)NC1(C)CNC1.[H]Cl

Description

tert-Butyl (3-methylazetidin-3-yl)carbamate hydrochloride delivers a stable, moisture-tolerant azetidine scaffold with a protected amine for facile deprotection. The tert-butyl carbamate group enables efficient handling and incorporation into complex molecular architectures. This bench-stable derivative facilitates rapid access to bioactive nitrogen-containing heterocycles in medicinal chemistry workflows.

Application

tert-Butyl (3-methylazetidin-3-yl)carbamate hydrochloride serves as a stable, bench-ready building block for the synthesis of bioactive azetidine-containing scaffolds. The carbamate group enables selective deprotection under mild acidic conditions, while the tertiary amine functionality supports efficient functionalization and incorporation into medicinal chemistry libraries. Its structural rigidity and defined stereochemistry facilitate reproducible transformations in peptide mimetics and heterocyclic drug discovery.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   50.36
  • LogP   1.2948
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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