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CS-W001157 4
Total: USD 88.00

trans-3-(Methylsulfonyl)cyclobutanamine hydrochloride

  • CAS No. 1408075-97-7

  • Cat. No. CS-0045553
  • Purity≥97%
  • MDL No.None
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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

trans-3-(Methylsulfonyl)cyclobutanamine hydrochloride|CS-0045553

Structure of 1408075-97-7

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Description

trans-3-(Methylsulfonyl)cyclobutanamine hydrochloride is a bench-stable, moisture-tolerant amine derivative featuring a rigid cyclobutane scaffold. The methylsulfonyl group imparts high polarity and solubility, while the hydrochloride salt ensures enhanced handling and crystallinity. This compound integrates readily into medicinal chemistry libraries for targeted bioactive molecule synthesis.

Application

trans-3-(Methylsulfonyl)cyclobutanamine hydrochloride serves as a versatile, bench-stable building block for medicinal chemistry and process development. Its constrained cyclobutane scaffold imparts conformational rigidity, while the methylsulfonyl group provides excellent solubility and metabolic stability. The amine functionality enables straightforward derivatization via reductive amination, amidation, or coupling reactions, facilitating rapid access to diverse heterocyclic and bioactive scaffolds in drug discovery campaigns.

General Information

  • CAS No. 1408075-97-7
  • Cat. No. CS-0045553
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₂ClNO₂S
  • Molecular Weight 185.67
  • Synonym(s) trans-3-MethylsulfonylcyclobutylaMine hydrochloride
  • SMILES N[C@H]1C[C@H](S(=O)(C)=O)C1.[H]Cl

Computational Chemistry Data

  • TPSA   60.16
  • LogP   -0.0575
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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