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CS-W001157 4
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Boc-azetidine-cyclohexanamine

  • CAS No. 1408075-19-3

  • Cat. No. CS-0042477
  • Purity≥98%
  • MDL No.MFCD21648502

*For research and further manufacturing use only, not for direct human use.

Boc-azetidine-cyclohexanamine|CS-0042477

Structure of 1408075-19-3

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General Information

  • CAS No. 1408075-19-3
  • Cat. No. CS-0042477
  • Purity ≥98%
  • MDL No. MFCD21648502
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₄N₂O₂
  • Molecular Weight 240.35
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)N1CC2(C1)CCC(N)CC2

Description

tert-Butyl 7-amino-2-azaspiro[3.5]nonane-2-carboxylate delivers a rigid, nitrogen-rich spirocyclic scaffold ideal for medicinal chemistry. This bench-stable intermediate features a primary amine at the 7-position and a protected carboxylic acid, enabling direct functionalization and incorporation into complex heterocycles.

Application

tert-Butyl 7-amino-2-azaspiro[3.5]nonane-2-carboxylate serves as a versatile spirocyclic scaffold for medicinal chemistry, enabling efficient access to constrained piperidine analogs. The protected amine and carboxylate groups offer orthogonal reactivity, facilitating modular derivatization via amidation, alkylation, or reduction. Bench-stable and readily purified by chromatography, it functions as a key building block in the synthesis of bioactive heterocycles and API intermediates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   55.56
  • LogP   2.1248
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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