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CS-W001157 4
Total: USD 88.00

(S)-1-(2-Bromophenyl)ethanamine

  • CAS No. 140632-12-8

  • Cat. No. CS-0000338
  • Purity≥97%
  • MDL No.MFCD06761911

*For research and further manufacturing use only, not for direct human use.

(S)-1-(2-Bromophenyl)ethanamine|CS-0000338

Structure of 140632-12-8

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General Information

  • CAS No. 140632-12-8
  • Cat. No. CS-0000338
  • Purity ≥97%
  • MDL No. MFCD06761911
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀BrN
  • Molecular Weight 200.08
  • Synonym(s) (S)-2-Bromo-alpha-methylbenzenemethanamine
  • SMILES BrC1=CC=CC=C1[C@H](C)N

Description

(S)-1-(2-Bromophenyl)ethanamine is a chiral building block featuring a brominated aromatic ring and a stereogenic center. This bench-stable amine integrates readily into asymmetric synthesis, serving as a precursor for pharmaceutical intermediates and ligands in transition-metal catalysis.

Application

(S)-1-(2-Bromophenyl)ethanamine serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of asymmetric pharmaceutical intermediates. Its benzylic amine functionality facilitates direct functionalization and coupling reactions, while the ortho-bromo substituent provides a handle for palladium-catalyzed cross-couplings. The compound exhibits good bench stability and compatibility with standard purification methods, making it suitable for scalable synthesis workflows.

Synthesis

  • Route1
    • null|null
      943779-19-9
    • ~82%
    • In-stock
      (S)-1-(2-Bromophenyl)ethanamine|CS-0000338
      140632-12-8

    References

    • Brenchley, Guy; Fedouloff, Michael; Merifield, Eric; Wills, Martin Tetrahedron Asymmetry, 1996 , vol. 7, # 10 p. 2809 - 2812
  • Route2

    References

    • Tetrahedron Asymmetry, , vol. 7, # 10 p. 2809 - 2812
  • Route3

    References

    • Tetrahedron Asymmetry, , vol. 7, # 10 p. 2809 - 2812

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.4688
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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