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Structure of 14062-30-7
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Ethyl 2-(3-bromophenyl)acetate features a brominated phenyl ring flanked by an ethyl ester and a methylene bridge, enabling direct functionalization at the ortho position. This configuration supports efficient coupling reactions in cross-coupling protocols and facilitates the synthesis of complex aromatic scaffolds under mild conditions.
Ethyl 2-(3-bromophenyl)acetate serves as a versatile building block for C–C coupling reactions, enabling efficient access to biaryl and heteroaryl scaffolds. Its brominated aryl group facilitates palladium-catalyzed cross-coupling with boronic acids, stannanes, and other nucleophiles under standard conditions. The ester functionality supports further transformations, including reduction to the alcohol or hydrolysis to the carboxylic acid, offering orthogonal reactivity in multi-step syntheses. Bench-stable and readily purified by column chromatography, it is well-suited for industrial R&D workflows requiring reliable functional group handling.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: